pentobarbital decreases outcomes of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Coadministration of CYP3A4 inducers could minimize sufentanil amounts and efficacy, maybe precipitating withdrawal syndrome in individuals which have produced Actual physical dependence to sufentanil. Discontinuation of concomitantly employed CYP3A4 inducers may perhaps enhance sufentanil plasma concentration.

Facts are currently not available to Appraise outcome of barbiturates when forceps shipping and delivery or other intervention is important; also, details aren't obtainable to find out the influence of such barbiturates on the later development, enhancement, and purposeful maturation of the kid

pentobarbital will lessen the level or outcome of bexarotene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

pentobarbital will reduce the level or influence of ixabepilone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.

pentobarbital will decrease the extent or impact of solifenacin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

pentobarbital will increase toxicity of ifosfamide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. CYP3A4 inducers could increase the metabolism of ifosfamide to its Lively alkylating metabolites.

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pentobarbital will lower the extent or effect of lorlatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will decrease the extent or influence of verapamil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.

Warning when discontinuing CYP3A4 inducers that happen to be coadministered with hydrocodone; plasma concentrations of hydrocodone may perhaps maximize and may lead to most likely deadly respiratory melancholy

pentobarbital will minimize the level or effect of alfentanil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Mysterious.

pentobarbital will reduce the level or outcome of tacrolimus by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

pentobarbital will lower the level or impact of tipranavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

Contraindicated (1)pentobarbital will lessen the extent or impact of lumacaftor/ivacaftor by more info influencing hepatic/intestinal enzyme CYP3A4 metabolism.